TGFBI-related Corneal Dystrophies: Clinical Findings, Cell Biology, and Genetics

TGFBI-Related Corneal Dystrophies by Eung Kweon Kim and R. Doyle Stulting provides a comprehensive, up-to-date overview of corneal dystrophies associated with mutations in the TGFBI gene. This book covers the fundamental aspects of cell biology, protein processing, and genetics underlying these conditions, offering clinicians and researchers a detailed understanding of the pathogenesis, diagnosis, and potential treatment strategies, including emerging approaches in human gene therapy.

Key Features

• Cell Biology and Genetics: Explains the intracellular processing of both normal and mutated TGFBI proteins and their role in corneal pathology.
• Clinical Illustrations: Extensive images document the clinical presentation of various TGFBI-related corneal dystrophies.
• Pathogenesis Insights: Detailed discussion of metabolic pathways and the cellular mechanisms involved in disease progression.
• Therapeutic Approaches: Covers current management strategies and explores potential gene therapy options.
• Professional Utility: Serves as a practical resource for ophthalmologists, corneal specialists, and trainees seeking a thorough understanding of TGFBI-related disorders.

Product Details

• Publisher ‏ : ‎ Springer; 2025th edition (February 22, 2025)
• Language ‏ : ‎ English
• ISBN-10 ‏ : ‎ 9819601304
• ISBN-13 ‏ : ‎ 978-9819601301