Epidermal Langerhans Cells

Epidermal Langerhans Cells provides an authoritative exploration of epidermal Langerhans cells (LCs), key antigen-presenting cells in the skin that play pivotal roles in immune responses such as contact hypersensitivity and graft rejection. This text examines how LCs are influenced by physicochemical agents, including UV light, and how they can serve as targets for viral infections like HIV. It also details the cytokine-mediated development of LCs into potent T cell-stimulatory dendritic cells, offering insight into their immunological significance.

Key Features:

• In-Depth Review: Comprehensive coverage of the biology, function, and clinical relevance of epidermal Langerhans cells.
• Immune Modulation: Explores how LCs respond to environmental factors and pathogens, including viral infections.
• Experimental Insights: Details key methodologies and experimental findings relevant to LC research.
• Cytokine Regulation: Explains the role of cytokines in LC maturation and T cell activation.
• Clinical and Research Utility: Serves as an indispensable resource for dermatologists, immunologists, and researchers investigating antigen-presenting cells.

Product Details

• Publisher ‏ : ‎ CRC Press; 1st edition (December 26, 1990)
• Language ‏ : ‎ English
• ISBN-10 ‏ : ‎ 0849356466
• ISBN-13 ‏ : ‎ 978-0849356469