Allergic Contact Dermatitis

Allergic Contact Dermatitis by Camilla Smith offers a scientific and clinically relevant exploration of how xenobiotics—foreign chemicals found in everyday products—interact with the skin to trigger allergic responses. By integrating toxicology, dermatology, and skin biochemistry, the book provides an in-depth look at percutaneous absorption, cutaneous metabolism, and the molecular pathways involved in sensitization. It serves as an essential reference for understanding how substances in foods, cosmetics, pharmaceuticals, and other consumer products may lead to contact allergies, and how these risks can be identified and evaluated.

Key Features

• Detailed examination of xenobiotic metabolism, including how chemicals penetrate the skin and are transformed by metabolic processes.
• Insight into protein reactivity, explaining how sensitizers bind to skin proteins and initiate immune responses.
• Scientific discussion of sensitization pathways and how metabolic activity contributes to allergic outcomes.
• Evaluates chemical hazards commonly found in foods, cosmetics, topical products, and pharmaceuticals.
• Guidance on identifying potential allergens and understanding their toxicological profiles.
• Highly relevant for regulatory and safety professionals, offering concepts applicable to risk assessment, product development, and public health.
• A comprehensive one-stop resource for researchers in academia, dermatology, toxicology, industry, and governmental agencies.

Product Details

• Publisher: CRC Press; January 6, 2023
• Language: English
• ISBN 10 : 0415250471
• ISBN 13 : 978-0415250474